Book Review: When the World Collapses

Aging: when the ubiquitin–proteasome machinery collapses

In mammalian cells, protein degradation is an essential and dynamic process that is crucial for survival, growth, differentiation and proliferation of cells. Tellingly, the majority of intracellular proteins are degraded via the ubiquitin–proteasome system (UPS). UPS-mediated protein degradation serves qualitative and quantitative roles within the cellular proteome. For instance, UPS specifical...

Review Review of the World Class Parasites Book Series

1. Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK 2. Yale University School of Medicine, Department of Epidemiology and Public Health, USA. 3. Department of Microbiology/Immunology, University of Health Sciences/Chicago Medical School, USA 4. Instituto de Biologia Molecular do Parana, Fundação Oswaldo Cruz, Brazil 5. Instituto de Biofisica Car...

When the world collapses: changed worldview and social reconstruction in a traumatized community

BACKGROUND Traumatic experience can affect the individual's basic beliefs about the world as a predictable and safe place. One of the cornerstones in recovery from trauma is reestablishment of safety, connectedness, and the shattered schema of a worldview. OBJECTIVE This study explored the role of negatively changed worldview in the relationship between war-related traumatization and readines...

BOOK REVIEW When evo–devo transcends the etiological myth

How the Snake Lost its Legs is Lewis Held’s second essay approaching the theme of developmental evolution with a focus on natural oddities. His previous opus—Quirks of Human Anatomy: An Evo-Devo Look at the Human Body—unraveled the peculiarities and flaws of our own bodies in light of evo– devo research (Held 2009). In How the Snake Lost its Legs, Held directly delves into animal diversity to s...

Book Review: Safer Healthcare; Strategies for the Real World